Claus Bachert Selected Research

Interleukin-10 (Interleukin 10)

1/2022	IL-10 family cytokines in chronic rhinosinusitis with nasal polyps: From experiments to the clinic.
10/2021	Regulated on Activation, Normal T cell Expressed and Secreted (RANTES) drives the resolution of allergic asthma.
1/2021	Single-cell analysis pinpoints distinct populations of cytotoxic CD4+ T cells and an IL-10+CD109+ TH2 cell population in nasal polyps.
11/2018	Immunomodulatory effect of Bifidobacterium breve on experimental allergic rhinitis in BALB/c mice.
4/2015	Effect of budesonide transnasal nebulization in patients with eosinophilic chronic rhinosinusitis with nasal polyps.
2/2008	Role of staphylococcal superantigens in upper airway disease.
1/2008	Staphylococcus aureus enterotoxin B, protein A, and lipoteichoic acid stimulations in nasal polyps.

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Claus Bachert Research Topics

Disease

122	Nasal Polyps (Nasal Polyp) 05/2024 - 11/2003
116	Rhinosinusitis 05/2024 - 09/2003
92	Asthma (Bronchial Asthma) 01/2024 - 05/2003
80	Inflammation (Inflammations) 01/2024 - 11/2002
41	Allergic Rhinitis 01/2022 - 09/2002
32	Hypersensitivity (Allergy) 01/2023 - 06/2005
31	Polyps 07/2023 - 11/2003
13	Infections 01/2023 - 01/2011
13	Rhinitis 12/2020 - 10/2004
12	Seasonal Allergic Rhinitis (Hay Fever) 01/2018 - 04/2003
8	Atopic Dermatitis (Atopic Eczema) 01/2023 - 05/2002
7	Edema (Dropsy) 01/2024 - 05/2009
6	Neoplasms (Cancer) 12/2022 - 11/2017
6	Eosinophilia 11/2022 - 01/2013
6	Nasal Obstruction 01/2022 - 05/2009
6	COVID-19 01/2022 - 05/2020
6	Rhinorrhea 01/2020 - 10/2004
5	Anosmia 08/2023 - 03/2011
5	Chronic Obstructive Pulmonary Disease (COPD) 01/2023 - 09/2004
5	Pruritus (Itching) 01/2022 - 10/2004
5	Allergic Fungal Sinusitis 12/2015 - 11/2006
5	Cystic Fibrosis (Mucoviscidosis) 01/2015 - 10/2009
4	Chronic Urticaria 01/2023 - 11/2005
4	Eczema 01/2022 - 04/2007
4	Sneezing 11/2018 - 10/2004
4	Perennial Allergic Rhinitis 04/2015 - 09/2002
3	Pneumonia (Pneumonitis) 01/2023 - 05/2011
3	Respiratory Tract Infections (Respiratory Tract Infection) 01/2023 - 07/2005
3	Headache (Headaches) 01/2021 - 06/2004
3	Chronic Disease (Chronic Diseases) 12/2020 - 09/2004
3	Hyperplasia 01/2018 - 05/2011
3	Urticaria (Hives) 10/2016 - 09/2002
3	Facial Pain (Myofacial Pain) 01/2012 - 03/2011

Drug/Important Bio-Agent (IBA)

63	Immunoglobulin E (IgE)IBA 01/2024 - 11/2002
43	CytokinesIBA 01/2024 - 01/2005
32	Enterotoxins (Enterotoxin)IBA 11/2023 - 11/2002
30	Interleukin-5 (Interleukin 5)IBA 01/2024 - 03/2004
28	dupilumabIBA 01/2024 - 12/2015
27	AllergensIBA 01/2022 - 01/2009
23	Adrenal Cortex Hormones (Corticosteroids)IBA 01/2024 - 09/2002
22	Biomarkers (Surrogate Marker)IBA 05/2024 - 04/2012
19	Proteins (Proteins, Gene)FDA Link 08/2021 - 09/2004
17	Interleukin-13IBA 01/2024 - 01/2008
15	AntibodiesIBA 12/2020 - 11/2003
14	Aspirin (Acetylsalicylic Acid)FDA LinkGeneric 01/2023 - 03/2004
12	Interleukin-4 (Interleukin 4)IBA 01/2024 - 01/2008
12	InterleukinsIBA 01/2024 - 11/2002
12	SuperantigensIBA 12/2020 - 05/2002
10	Omalizumab (Xolair)FDA Link 07/2023 - 01/2009
8	Anti-Bacterial Agents (Antibiotics)IBA 01/2023 - 12/2005
8	Monoclonal AntibodiesIBA 10/2022 - 01/2019
8	Messenger RNA (mRNA)IBA 01/2021 - 06/2005
7	mepolizumabIBA 01/2024 - 12/2015
7	Nasal SpraysIBA 01/2022 - 09/2002
7	Interleukin-10 (Interleukin 10)IBA 01/2022 - 01/2008
7	Mometasone Furoate (Nasonex)FDA LinkGeneric 01/2022 - 09/2005
7	Eosinophil Cationic ProteinIBA 01/2013 - 06/2005
6	Immunoglobulins (Immunoglobulin)IBA 11/2023 - 02/2008
6	ChemokinesIBA 04/2022 - 01/2005
6	SteroidsIBA 01/2020 - 11/2003
6	desloratadine (Aerius)FDA LinkGeneric 01/2012 - 09/2007
6	levocetirizine FDA LinkGeneric 11/2011 - 10/2004
5	Peptide Hydrolases (Proteases)FDA Link 01/2023 - 01/2018
5	Interleukin-33IBA 01/2023 - 01/2018
5	azelastine (Optivar)FDA LinkGeneric 12/2020 - 11/2011
5	anti-IgE antibodiesIBA 01/2020 - 01/2009
5	Transforming Growth Factor beta (TGF-beta)IBA 01/2018 - 05/2002
5	Histamine Antagonists (Antihistamines)IBA 04/2015 - 06/2004
4	PeriostinIBA 08/2021 - 12/2015
4	Fluticasone (Cutivate)FDA LinkGeneric 12/2020 - 05/2012
4	SmokeIBA 01/2020 - 07/2010
4	CollagenIBA 04/2015 - 08/2009
4	Peroxidase (Myeloperoxidase)IBA 01/2013 - 07/2006
4	fexofenadine (Allegra)FDA LinkGeneric 11/2011 - 04/2003
4	LeukotrienesIBA 04/2009 - 06/2005
3	Bronchodilator Agents (Bronchodilators)IBA 10/2023 - 01/2022
3	Interleukin-6 (Interleukin 6)IBA 06/2023 - 01/2013
3	1-phenyl-3,3-dimethyltriazene (PDT)IBA 12/2022 - 12/2019
3	Tryptases (Tryptase)IBA 01/2022 - 04/2009
3	Complement System Proteins (Complement)IBA 01/2022 - 09/2009
3	Matrix Metalloproteinases (MMPs)IBA 08/2021 - 05/2010
3	Toll-Like Receptors (Toll-Like Receptor)IBA 03/2021 - 05/2009
3	Adenosine Triphosphate (ATP)IBA 01/2021 - 12/2019
3	HMGB1 Protein (HMG1)IBA 01/2021 - 12/2019
3	Immunoglobulin G (IgG)IBA 01/2019 - 01/2011
3	Peptides (Polypeptides)IBA 01/2019 - 04/2010
3	TabletsIBA 12/2018 - 11/2014
3	GlucocorticoidsIBA 04/2015 - 05/2010
3	MP29-02IBA 04/2015 - 05/2012
3	Histamine (Histamine Dihydrochloride)FDA Link 11/2011 - 04/2009
3	EicosanoidsIBA 04/2008 - 06/2005
3	Transforming Growth Factor beta1 (TGF beta 1)IBA 02/2008 - 09/2004
2	benralizumabIBA 05/2024 - 01/2022
2	TenascinIBA 01/2024 - 08/2021
2	Non-Steroidal Anti-Inflammatory Agents (NSAIDs)IBA 12/2023 - 01/2022
2	RNA (Ribonucleic Acid)IBA 11/2023 - 09/2004

Therapy/Procedure

41	Therapeutics 01/2024 - 09/2005
11	Drug Therapy (Chemotherapy) 01/2022 - 01/2012
11	Immunotherapy 01/2021 - 01/2009
4	Precision Medicine 01/2021 - 01/2017